期刊文献+

慢性阻塞性肺疾病系统性炎症的治疗进展 被引量:2

Progress on treatment of systemic inflammation of chronic obstructive pulmonary disease
原文传递
导出
摘要 慢性阻塞性肺疾病机制复杂,不仅表现为肺部的局部炎症,而且存在系统性炎症反应,后者导致一些肺外器官受损.目前,正在研究针对于控制系统性炎症的新的治疗方法.综述了治疗COPD患者系统性炎症的新方法. Chronic obstructive pulmonary disease (COPD) is a complex disorder,characterized not only by local pulmonary inflammation, but also by systemic inflammation that might have an adverse impact on various extrapulmonary organs. Now several new therapeutic strategies aimed at controlling the systemic inflammatory processes of COPD are under development. This review is to introduce the advanced progress in the treatment aimed at systemic inflammation in COPD patients.
出处 《国际呼吸杂志》 2010年第22期1403-1406,共4页 International Journal of Respiration
关键词 慢性阻塞性肺疾病 系统性炎症 Chronic obstructive pulmonary disease Systemic inflammation
  • 相关文献

参考文献24

  • 1Agusti A.Chronic obstructive pulmonary disease:a systemic disease.Proc Am Thorae Soc,2006,3:478-481.
  • 2Kilfeather S.5-Lipoxygenase Inhibitors for the Treatment of COPD.Chest,2002,121 (5 Suppl):197s-200s.
  • 3Yokomizo T,Izumi T,Shimizu T.Leukotriene B4:metabolism and signal transduction.Arch Biochem Biophys,2001,385:231-241.
  • 4Hill AT,Bayley D,Stockley RA.The interrelationship of sputum inflammatory markers in patientswith chronic bronchitis.Am J Respir Crit Care Med,1999,160:893-898.
  • 5Silbaugh SA,Stengel PW,Cockerham SL,et al.Pharmacologic actions of the second generation leukotriene B4 receptor antagonist LY29311:invivo pulmonary studies.Naunyn Schmiedebergs Arch Pharmacol,2000,361:397-404.
  • 6Rabinowitz MH,Andrews RC,Becherer JD,et al.Design of selective and soluble inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).J Med Chem,2001,44:4252-4267.
  • 7Keatings VM,Collins PD,Scott DM,et al.Differences in interleukin-8 and tumornecrosis factor-α in induced sputum from patientswith chronic obstructive pulmonary disease or asthma.Am J Respir Crit Care Med,1996,153:530 534.
  • 8de Boer WI,Sont JK,van Schadewijk A,et al.Monocyte chemoattractant protein 1,interleukin 8,and chronic airways inflammation in COPD.J Pathol,2000,190:619-626.
  • 9白春学.COPD的炎症和抗炎研究进展[J].临床肺科杂志,2005,10(5):552-553. 被引量:11
  • 10Boswell-Smith V,Cazzola M,Page CP,et al.Are phosphodiesterase 4 inhibitors justmore theophylline?.J Allergy Clin Immunol,2006,117:1237-1243.

共引文献10

同被引文献50

引证文献2

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部