摘要
采用ＥＳＲ、自旋捕集及自旋氧探针技术，研究了海藻硫酸多糖（ＳＰＳ）对豆蔻酰佛波醇乙酯（ＰＭＡ）刺激的多形核白细胞（ＰＭＮ）呼吸爆发的影响．结果表明，ＳＰＳ能显著抑制ＰＭＮ呼吸爆发，１０ｇ／Ｌ和５ｇ／ＬＳＰＳ几乎完全清除ＰＭＮ呼吸爆发产生的自由基，１ｇ／ＬＳＰＳ可清除５３２％；
The influence of sulfated polysaccharide from brown seaweed Laminaria Japonica(SPS) on the respiratory burst of polymorphonuclear neutrophils(PMN) induced by phorbol myristate acetate(PMA) was investigated with the techniques of ESR,spin trap and oxygen spin probe.The results showed that SPS inhibited the respiratory burst of PMN significantly. 10 g/L and 5 g/L SPS almost completely scavenged superoxide anion (O · 2) from the respiratory burst while 10 g/L SPS inhibited the oxygen consumption of PMN markablely, and 1 g/L SPS scavenged 53 2% O · 2.
出处
《生物化学与生物物理进展》
SCIE
CAS
CSCD
北大核心
1999年第2期162-164,共3页
Progress In Biochemistry and Biophysics
基金
国家自然科学基金
关键词
海藻硫酸多糖
多形核白细胞
呼吸爆发
sulfated polysaccharide from brown seaweed(SPS),polymorphonuclear neutrophils(PMN),respiratory burst,superoxide anion(O · 2)
