益气养阴解郁法治疗糖尿病伴发抑郁症的临床研究

Qi-Yin Nourishing Method to Treat Diabetes with Depression

目的:客观评价益气养阴解郁法治疗糖尿病伴发抑郁症的临床疗效。研究方法:采用随机对照的试验方法随机分为治疗组33例,对照组32例。在维持原基础治疗的同时治疗组采用益气养阴疏肝解郁方(黄芪、太子参、柴胡、枳壳、白芍、酸枣仁等)治疗,对照组采用盐酸氟西汀治疗,疗程8周。结果:益气养阴解郁方能明显改善糖尿病伴发抑郁症患者的HAMD评分、改善患者神疲乏力、少气懒言、忧愁善感、烦躁易怒等临床症状症状,总有效率达到83.33%,明显优于对照组66.67%。结论:益气养阴解郁方治疗糖尿病伴发抑郁症是安全有效的方药,值得进一步推广和应用。

Objective：To evaluate efficacy of Qi-Yin Nourishing Method to treat diabetes with depression.Methods：Using randomization,treatment group took Qi-Yin Nourishing formula（ingredients：Huangqi,Taizishen,Chaihu,Zhiqiao,Baishao,Suanzaoren,etc.）in addition to basic treatment,control group took Fluoxetine hydrochloride,for 8 weeks.Results：Qi-Yin Nourishing formula can significantly improve HAMD score,alleviate such symptoms as lassitude,weakness,shortness of breath,melancholy,irritability,with a total effective rate of 83.33%,compared to 66.67% that of control group.Conclusion：Qi-Yin Nourishing formula is safe and effective for treating diabetes with depression,and suitable for clinical application.