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1,25-二羟维生素D3与自身免疫性疾病 被引量：3

1,25-Dihydroxyvitamin D3 and autoimmune diseases
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摘要 1,25-二羟维生素D3对T细胞、B细胞、巨噬细胞、树突状细胞和角化细胞等均有调节作用,并与许多自身免疫性疾病包括类风湿性关节炎、青少年糖尿病、克罗恩病、多发性硬化等密切相关.1,25-二羟维生素D3可能成为治疗自身免疫性疾病的药物之一,但最佳用药剂量及疗程尚需进一步研究. 1,25-dihydroxyvitamin D3 plays a role in the regulation of T cells, B cells, macrophages,dendritic cells,and keratinocytes. 1,25-dihydroxyvitamin D3 is linked to many autoimmune diseases, including rheumatoid arthritis,juvenile diabetes, Crohn＇s disease, multiple sclerosis. It may have potential as a treatment for autoimmune diseases, however, additional research will focus on better quantify dosage and course of treatment.
作者 邹敏书(综述) 余健(审校)
机构地区 广州军区武汉总医院儿科
出处 《国际儿科学杂志》 2010年第6期625-627,共3页 International Journal of Pediatrics
关键词 1 25-二羟维生素D3 T细胞 B细胞 自身免疫性疾病 1,25-Dihydroxyvitamin D3 T cell B cell Autoimmune diseases
分类号 R977.24 [医药卫生—药品]
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参考文献23

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国际儿科学杂志
2010年 第6期

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