摘要
为探讨吸烟对胚泡发育的影响,观察了烟草凝集物(CSC)对孕7天兔胚泡的过氧化脂质(LPO)和乳酸脱氢酶(LDH)的影响。结果表明,体外培养4h时LPO水平比2h显著升高(P<0.05),4hLDH与2hLDH相比差异不显著。LDH活力与CSC剂量不相关,但LPO有随CSC剂量增加而上升的趋势,其r值接近P=0.05的显著性水平。提示CSC有促进脂质过氧化反应的趋势。
To study the effects of smoking on the development of blastocysts,the activities of lactic dehydrogenase (LDH) and the levels of lipid peroxides(LPO) in blastocysts of 7daypregnancy age rabbits exposed to cigarette smoking condensate (CSC) were determined in vitroThe results showed that the levels of LPO increased significantly in the blastocysts exposed to CSC for 4 hours compared with those for 2 hoursThe activities of LDH revealed no significant variances when the blastocysts were exposed to CSC for 2 hours and 4 hoursThe activities of LDH presented no significant correlation with the exposure levels of CSCWhile,there was a tendency that the levels of LPO increased with the the increase of CSC,their r value approach to the significant level of P=005It indicated that there was a tendency that CSC could accelerate the lipid peroxidation in blastocysts
出处
《环境与健康杂志》
CAS
CSSCI
CSCD
北大核心
1999年第4期187-188,共2页
Journal of Environment and Health
基金
国家计划生育委员会资助