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CT灌注成像在急性脑梗死中的应用价值

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摘要 目的:应用CT灌注成像研究急性脑梗死(acute cerebral infarction,ACI)早期的成像特点。方法采用32排螺旋CT对36例急性脑梗死患者,行CT平扫和CT灌注成像检查,并于48小时后复查头颅CT,定量分析梗死中心区域与缺血半暗带、病灶区与对侧相应区域脑血容量(cerebral blood volume,CBV)、脑血流量(cerebral blood flow,CBF)、达峰时间(time to peak,TP),并进行比较。结果:36例患者中,首次常规CT检查有9例显影,灌注CT成像有26例显影,其中除1例过度灌注外,其余均为病侧CBV、CBF较对侧减低,TP较对侧延长,病灶整体区CBV(3.38±0.77)ml/g低于对侧(4.56±1.59)ml/g(P〈0.05),CBF(17.03±5.13)ml·min^-1·100g^-1显著低于对侧(29.12±6.78)ml·min^-1·100g^-1(P〈0.01),TP(25.03±5.08)s较对侧(21.96±5.20)s延长(P〈0.05);梗死中心区CBV(1.36±0.76)ml/g,CBF(6.45±2.63)ml·min^-1·100g^-1显著低于缺血半暗带区CBV(3.86±1.32)ml/g,CBF(20.43±4.54)ml·min^-1·100g^-1(均P〈0.01),TP(30.52±2.63)s较缺血半暗带区(22.82±5.60)s显著延长(P〈0.01),差异均具有统计学意义。结论:灌注CT能够在急性脑梗死早期清楚地显示病变部位,范围和缺血程度,明确半暗带的存在及灌注情况,并进行定量研究,对超早期是否采取溶栓治疗具有一定的指导价值。
出处 《中国中医药咨讯》 2010年第32期264-265,共2页
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参考文献6

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