112卵巢过度刺激综合征的治疗及妊娠结局分析

Clinical analyses for 112 patients of ovarian hyperstimulation syndrome

目的:探讨辅助生殖技术中的卵巢过度刺激综合征(OHSS)的治疗方法及对妊娠结局的影响。方法:对我院128例OHSS患者临床资料进行回顾性分析。结果:OHSS发生率13.11%(128/976),其中轻度9.22%(90/976),中、重度3.89%(38/976);所有OHSS患者住院5～47天均康复出院;促排卵治疗周期与OHSS患者妊娠率有显著性差异(P<0.05);①71例临床妊娠中,妊娠丢失10例(14.08%),继续妊娠61例(85.92%)。②轻度OHSS与中、重度OHSS患者两组间妊娠丢失率有显著性差异(P<0.05)。③OHSS患者妊娠后多胎妊娠丢失率较单胎妊娠高(P<0.05)。结论:OHSS为促排卵引起的严重并发症,应予正确防治和保胎治疗,减轻患者痛苦。

Objective ：To investigate the therapy method of ovarian hyperstimulation syndrome of assisted reproductive technology and the influences to pregnancy outcome. Methods：We analyze retrospectively 128 pacients of ohss in our hospital. Result：The incidence rate of ohss is 13.11% （ 128/976 ）, among which ,9.22% is mild ohss,3.89% is;All the patients of ohss have been in hospital for 5 -47 days and rehabitation discharged; there is significant difference between the cycle of ovula- tion stimulants therapy and the pregnancy rate of the pacients of ohss. （P 〈 0.05） ①Arnong the 71 patients of clinic encyesis,pregnaney loss was （14.08%） ,61 patients continue to eneyesis. ②There is significant difference in pregnancy loss between the mild ohss and midst severe ohss. ③The loss rate of multifetation of the pacients of OHSS is higher than monocyesis. Conclusion： Ohss is a severely complication of ovulation stimulants, we should give right prevention and cure, tocolysis, and reduce the pain of the patiences.