新疆地区高脂血症中医证候类型因子分析

Factor Analysis on the Distribution of Chinese Medicine Syndromes in Patients with Hyperlipidemia in Xinjiang Region

目的寻找出新疆地区高脂血症基本症状的分布规律。方法对新疆地区高脂血症患者应用临床辨证分型的方法,寻找高脂血症辨证分型类别,使用因子分析的方法,提取支配高脂血症诊断信息的公因子,并根据中医理论和专家经验对其进行分析,以确定高脂血症证候辨证分型。结果新疆地区的高脂血症主要分为脾肾两虚精不足证、气血两虚证、肺卫燥证、痰湿蕴肺证、湿热壅滞证、肝肾阴虚血瘀证等;其中气血两虚证最为常见(35.09%),其次是肺卫燥证(29.82%)和脾肾两虚精不足证(13.45%)。6类证候积分比较,差异有统计学意义(F=32.746,P<0.01)。脾肾两虚精不足证病情程度较其他5类重,其次为肝肾阴虚血瘀证。结论新疆地区高脂血症以虚为主,兼见气滞、血瘀等证,呈现为涉及多脏器、气血津液俱病的复杂态势。

Objective To investigate the distributive rule of Chinese medicine syndromes in patients with hyperlipidemia（HLE） in Xinjiang region.Methods Chinese medicine syndrome of HLE patients were differentiated.The common factors of diagnostic information for dominating HLE were extracted by factor analysis and the syndrome type was determined based on Chinese medicine theory and experiences of experts.Results The syndromes in HLE patients of Xinjiang region were mainly the Pi-Shen deficiency with insufficient Jin syndrome（Ⅰ）,the qi-blood deficiency syndrome（Ⅱ）,the Fei-Wei dryness syndrome（Ⅲ）,the phlegm-dampness obstructing Fei syndrome（Ⅳ）,the dampnessheat accumulation syndrome（Ⅴ）,and the Gan-Shen yin-deficiency with blood-stasis syndrome（Ⅵ）.Syndrome Ⅱ was the most commonly encountered one（35.09%）,the next were syndrome Ⅲ（29.82%） and Ⅰ（13.45%）.Scores of the 6 syndromes,which embodied the severity of disease,were different significantly（F=32.746,P0.01）,the highest presented in syndrome Ⅰ and the second in Syndrome Ⅵ.Conclusions syndrome in hyperlipidemia patients of Xinjiang region is dominantly the deficiency syndrome,combined with qi-stagnancy and blood-stasis,showing a complex state involving multiple organs and all the qi,blood and Jin-Ye in body.