重度脑外伤急性期后生长激素变化及影响因素

The change of growth hormone after acute period of severe traumatic brain injury and its influential factors

目的:探讨重度脑外伤急性期后生长激素变化并寻找其影响因素。方法:选取70例重度脑外伤患者,测量基础生长激素值,计算异常发生率,并将受试对象分为正常组与异常组,评估两组在六项评估因素方面的差异。结果:重度脑外伤急性期后生长激素异常总发生率为47.1%;其异常变化与颅底骨折和病程密切相关。结论:重度脑外伤急性期后生长激素缺乏发生率高;其变化与不同相关因素相关。

Objective：To observe the changes of patient＇s growth hormone （GH） after acute period of severe traumatic brain injury（TBI）,and find out the influential factors of the changes of GH. Method：Seventy patients with severe TBI were selected, the basic levels of patients＇ GH were measured, and the abnormal rate was calculated. The objects were divided into normal team and abnormal team, to evaluate the difference between the two teams six evaluation factors. Result：The total abnormal incidence of Girl after acute period of severe TBI was 45.7%; basicranial fracture and the course of disease were related to GH abnormality. Conclusion：The abnormal incidence of GH after acute period of severe TBI was high; The hormone changes were associated with different factors.