慢性阻塞性肺疾病中医病机特点及“从肠论治”的理论探讨

Discussion on pathogenesis of COPD and treatment based on intestine

慢性阻塞性肺疾病(COPD)是临床常见病、多发病,其病因复杂、发病机制尚不明确,临床缺乏有效治疗手段。文章结合古今文献对COPD的中医学发病机制及其中医证候分布规律的研究,归纳出本虚标实是COPD的根本病机,瘀阻肺络、痰阻气机肺气不宣是导致COPD病势深伏并呈进行性发展的关键环节。临床辨治中,在整体辨证的基础上,应重视化痰消瘀,并提出基于"肺与大肠相表里"理论,合理采用通利大肠之法,将有助于改善COPD患者痰阻络瘀、肺气不宣的病理状态,减少CPOD反复急性发作、改善生活质量。

Chronic obstruetive oulmonary oisease （COPD） is a common and frequent disease, which has complicated etiology and the pathogenesis is undefinite, not effective therapeutic strategy for it. After exploring the TCM pathogenic factors and pathogenesis and the syndrome distribution regularity of Endometriosis （EMT） based on ancient and contemporary research, we generalize that the essence pathogenesis of COPD is deficiency in origin and excess in superficiality, and stagnation of phlegm, Lung-collateral obstruction, luggishness of lung-qi is key point which can cause the disease trend of maintain maintains restraint and progressive. So we should stress resolve phlegm and remove blood stasis exclusive of integral syndrome differentiation in clinical, and put forward that adopting catharsis large intestine rationally guided by the theory of the Lung and the Large Intestine Are Interior-Exteriorl can ameliorate stagnation of phlegm and blood and luggishness of lnng-qi, reduce exacerbated recurrence of COPD, inprove quality of life.