载脂蛋白模拟肽的研究进展

Research Progress of Apolipoprotein Mimetic Peptides

载脂蛋白模拟肽是利用现代生物技术合成的与载脂蛋白功能相当而分子量更小的一类多肽。应用这类模拟肽治疗动脉粥样硬化及其相关性疾病已成为近年来心血管疾病治疗领域的研究热点。本文就载脂蛋白模拟肽最新研究进展做一综述。

Apolipoprotein mimetic peptides that mimic the function of apolipoprotein with or without bearing the sequence homology to apolipoprotein have become a hot topic of atherosclerosis therapy research.The importance of apolipoprotein mimetic peptides in atherosclerosis and related disease was established by testing in animal models,and its potential usefulness in humans has been confirmed in preliminary studies.In this article,the development of apolipoprotein mimetic peptides is reviewed.