摘要
严重急性呼吸综合症(SARS)冠状病毒可以同时诱导出体液免疫应答和细胞免疫应答。对SARS康复者血清中特异性抗体水平检测表明,其随时间推移明显降低。特异性细胞免疫应答在机体清除病毒的过程中发挥着重要的作用,尤其是特异性记忆T细胞在抵御病毒再次入侵时,能迅速产生免疫应答有效保护机体。
Both of humoral and cellular immune responses can be induced by SARS coronavirus. It has been reported that the level of specific antibody is reduced in a time-dependent manner in SARS recovered patients. Cellular immune response plays an important role in antiviral immunity. Immune responses can be quickly produced by antigen-specific memory T cells to protect bodies against viruses. In this review, we summarize the recent progress of the production, maintenance and function of SARS antigen specific memory T cells.
出处
《国际免疫学杂志》
CAS
北大核心
2010年第6期427-430,共4页
International Journal of Immunology
基金
国家科技部“863”项目(2007AA022415)