加巴喷丁治疗带状疱疹后遗神经痛疗效

Efficacy of gabapentin in treating residual neuralgia of herpes zoster

目的探讨加巴喷丁对带状疱疹后遗神经痛的疗效。方法带状疱疹后遗神经痛患者46例,随机分为两组:A组24例,在常规治疗基础上加用加巴喷丁;B组22例,常规治疗加用卡马西平治疗。采用视觉模拟评分(VAS)进行疼痛评估,评价两组疗效。结果 A组临床治疗有效率为87.50%,明显高于B组的68.18%(P<0.05)。结论加巴喷丁治疗带状疱疹后遗神经痛疗效优于卡马西平,且疗效持久,副作用少而轻微。

Objective To observe the efficacy of gabapentin in treating residual neuralgia of herpes zoster.Methods Fourty-six patients with residual neuralgia of herpes zoster were randomly divided into two groups.The patients in group A（24 cases）were treated with gabapentin plus conventional therapy and those in group B with carbamazepine plus conventional therapy.Visual analogue scale（VAS）was used to evaluate the efficacy.Results Clinical efficacy was better in group A than that in group B.Conclusion Gabapentin is effective and better than carbamazepine in treating the residual neuralgia of herpes zoster.