富硒平菇干粉对小鼠的脏器指数与抗氧化能力的影响

Effect of Se-enriched Pleurotus ostreatus on organ index and anti-oxidative capability of rats

目的探讨富硒平菇干粉对小鼠的脏器指数与抗氧化能力的影响。方法将60只20g左右的健康昆明种小鼠随机分为6组。1组为对照组;2组为亚硒酸钠组;3组为普通平菇干粉组;4～6组为富硒平菇干粉组,分别在基础日粮中添加低、中、高浓度的富硒平菇干粉。30d后测定小鼠脏器指数与肝脏和血浆中谷胱甘肽过氧化物酶(GSH-Px)、超氧化物歧化酶(SOD)和丙二醛(MDA)含量。结果富硒平菇干粉可显著提高小鼠脾脏、胸腺和肝体指数;可显著提高小鼠肝脏与血浆中GSH-Px、SOD的酶活,降低小鼠肝脏和血浆中MDA含量。结论富硒平菇干粉可显著提高小鼠脏器指数与抗氧化能力。

Objective To study the effects of Se-enriched Pleurotus ostreatus on organ index and anti-oxidative capability of rats. Method Sixty healthy Kunming rats with about 20 g body weight were divided into six groups ： control group, Na2SeO3 group, normal Pleurotus ostreatus group, as well as Se-enriched Pleurotus ostreatus groups of low dose, medial dose and high dose, and the organ index and contents of GSH-Px, SOD and MDA in liver and plasma of mice were investigated after 30 days. Result Se-enriched Pleurotus ostreatus powder obviously increased the indice of Spleen, thymus and hepatosomatic, as well as GSH-Px and SOD activity in plasma and livers of rats ; meanwhile decreased significantly the MDA content in plasma and liver. Conclusion Se-enriched Pleurotus ostreatus powder can obviously increase the organ index and anti-oxidative capability.