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人乳头瘤病毒感染、中心体异常与宫颈癌 被引量:3

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摘要 宫颈癌(cervi calcancer)是发生于子宫颈鳞状上皮或腺上皮最常见的女性生殖道恶性肿瘤之一.流行病学和基础研究已证实人乳头瘤病毒(human papillomavirus,HPV)持续感染是导致宫颈癌发生的一个关键因素。近年来,许多学者在分子生物学领域对HPV致癌机制进行深入研究发现.HPV感染致宫颈上皮细胞中心体异常.使染色体错误分离及分配不平衡。导致染色体不稳定和非整倍体的形成。可能是其最终致癌的重要机制之一。
出处 《实用医学杂志》 CAS 北大核心 2010年第22期4230-4232,共3页 The Journal of Practical Medicine
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