上海地区81家医院2006～2009年抗感染药利用分析

Analysis of the Utilization of Anti-infective Agents in 81 Hospitals of Shanghai Area during the Period of 2006～2009

目的:了解上海地区医院抗感染药的应用情况和变化趋势,为临床合理应用抗感染药及科学管理提供参考。方法:调查上海地区81家医院2006～2009年抗感染药的销售金额、主要品种、用药频度(DDDs)及日均费用。结果:该地区抗感染药销售金额呈逐年上升趋势,年复合增长率达21.05%。DDDs和销售金额排序列前2位的均为头孢菌素类和喹诺酮类。头孢呋辛和阿奇霉素分列销售金额和DDDs的首位。注射剂销售金额远高于口服剂型,DDDs和销售金额排序列首位的都是国内生产厂家。结论:该地区医院抗感染药应用情况与国内、外总体用药情况相似,根据药敏结果选择品种是进一步提高抗感染药合理应用的关键。

OBJECTIVE： To investigate the utilization and tendency of anti-infective agents in 81 hospitals of Shanghai area during the period of 2006-2009, and to provide reference for rational use and scientific management of anti-infective agents in the clinic. METHODS： The utilization of anti-infective agents in 81 hospitals of Shanghai during 2006-2009 were investigated in respect of consumption sum, kinds of drugs, DDDs and DDC. RESULTS： The consumption sum of anti-infective agents in Shang- hai area during 2006-2009 increased year by year, and its compound annual growth rate was 21.05%. The cephalosporins and quino- lones ranked at the first two places in terms of consumption sum and DDDs. Cefuroxime occupied the first place in terms of consump- tion sum and azitromycin occupied the first place in the list of DDDs. The consumption sum of injective anti-infective agents was much more than that of oral agents. The domestic manufacturers took the lead in term of consumption sum and DDDs. CONCLUSION：The utilization of anti-infective agents in Shanghai is basically in line with the general medication situation at home or abroad. The selection of anti-infective agents according to drug susceptibility test is the key to improve rational use of anti-infective agents.