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新辅助化疗PVB在局部晚期宫颈癌中的应用

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摘要 目的:探讨新辅助化疗PVB方案对局部晚期型宫颈癌的疗效。方法:对2005年4月~2009年11月淄博市妇幼保健院妇科治疗的Ⅰb~Ⅱa期局部晚期宫颈癌患者进行分析,新辅助化疗(NACT)组45例,经过2~3个疗程的化疗后再进行根治性手术。对照组为未接受新辅助化疗而直接行根治性手术40例。术前评价NACT的疗效,并比较两组术中出血量、手术时间及术后病理情况。结果:NACT总有效率88.8%,NACT组与对照组术后标本病理检查发现两组淋巴结转移、宫旁浸润差异存在显著性,而在阴道切缘方面差异无显著性。NACT组较对照组术中出血、手术时间也存在显著性差异。结论:术前新辅助化疗对局部晚期宫颈癌有较好的临床疗效。
作者 张娟
出处 《中国社区医师(医学专业)》 2010年第34期71-71,共1页
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