规模化猪场仔猪黄、白痢的防治研究

Precaution and Therapy of Yellow and White Scour of Piglet in Large scale Pig Farm

本研究采用麦康凯、 Ｅ Ｍ Ｂ 选择性培养基对四川绵阳、乐山、南充、温江、自贡、广汉、德阳等地规模化猪场仔猪黄、白痢黄型病例进行了大肠杆菌分离培养， 对分离株进行了详细的生化鉴定， 并用小鼠作致病性试验， 获得８８ 株致病性大肠杆菌。对８８ 株大肠杆菌中的１９ 株用１０ 种抗生素进行了药敏试验， 结果表明： 分离菌株对恩诺沙星、环丙沙星、庆大霉素较敏感， 而对多种常用抗生素产生了不同程度的耐药性。对四川９ 个规模化猪场进行了本场菌株大肠杆菌灭活苗免疫试验， 取得良好效果。根据本研究结果提出： 采用本场菌株灭活苗免疫， 结合使用少量敏感抗生素， 并配合加强饲养管理等综合措施是防治规模化猪场仔猪黄、白痢最为经济有效的方法。

By utilizing altemative cultural medium such as Macconkek agar and Eosin Methylene Blue ahar(EMB)and pathogenic tests,88 pathogenic strains of E.coli were isolated and identified from the typical cases of yellow and white scour of piglet in the large scale pig farm of seven areas in Aichuan Procince.Then 19of 88 strains were performed the drug sensitivity test to select sensitive drugs.The result of drug sensitivithy shows that most isolated pathogenic bacteria strains were sensitive to Enrofloxacin Ciprofloxacin and Gentamycin,but had the resistance to the routinely used drug such as Terramycin and Furazolidone at different levels.The local isolated strains were used to make inactivated vaccine to immune the sow or piglet.this research shows that comprehensive mcasures including applying local bacteria strains to make vaccine to immmune pig,using the sensitive drug,improving the rearing management is the most economical and efficient way of preventing and therapying the yellow and scour of piglet in large scale pig farm