安徽省阜阳市危重症手足口病(EV71)病例对照研究

An case-control study of severe case of Hand-Foot-and-mouth disease (EV71) in Fuyang City,Anhui Province

目的探讨危重症手足口病(EV71)的主要危险因素,为防控手足口病提供依据。方法选取安徽省阜阳市手足口病危重症患儿85例为病例组,随机抽取57例轻症手足口病患儿为对照组。采用问卷法,调查患儿月龄、性别、出生状况、生长发育状况、既往病史、一般家庭情况和就诊经过等。结果手足口病危重症主要危险因素是患儿月龄、平时照看人、家庭月平均收入。结论患儿月龄小,平时由爷爷/奶奶或其他人照看,家庭月平均收入低,感染EV71后发生重症的可能大。

Objective To study the risk factors of severe and mild case of Hand-Foot-and-mouth disease（Enterovirus 71）.Methods Case-control stud y.85 severe cases of Hand-Foot-and-mouth disease（HFMD） were confirmed by the national,provincial and municipal Joint Group of Experts and 57 controls（mild cases） were included by questionnaire,questions about month-old children,sex,birth situation,growth and development situation,past medical history,general home situation and visit course,etc in Fuyang City.Results Risk factors for mild cases induce to severe case of HFMD were analyzed using multiple logistic regressions.It is month-old children,normally guardian and average incomes of families.Conclusions After children were infected by EV71,smaller month-old children,poorer average incomes of families and normally guardian was the Grandfather / Grandmother or other people,the more severe possible.