颅内钙化性表皮样囊肿影像与病理对照

Imaging Features of Intracranial Epidermoid Cyst with Calcification:A Comparative Analysis with Histopathology

目的 探讨颅内钙化性表皮样囊肿的影像学表现及其与临床病理的关系。资料与方法回顾性分析6例颅内钙化性表皮样囊肿的CT和MRI表现,并与临床手术、病理对照研究。结果 6例颅内钙化性表皮样囊肿中额叶1例,颞叶2例,顶叶1例,后颅窝1例,四脑室1例。6例病灶周围均无水肿,病灶内钙化呈蛋壳状1例,斑点状4例,弯曲条带状1例。钙化位于病灶中心1例,位于边缘5例。增强扫描病灶边缘轻到中度环形强化4例,无明显强化2例。6例病理结果均为表皮样囊肿伴炎性肉芽肿及钙化。结论 颅内钙化性表皮样囊肿少见,病理多提示合并感染,增强扫描可以强化,仔细分析其影像学表现,有助于提高术前诊断准确率。

Objective To investigate the correlation between the imaging features and pathological findings of calcified intracranial epidermoid cysts.Materials and Methods CT and MR imaging findings of 6 patients with intracranial calcified epidermoid cyst were analyzed retrospectively and correlated with operative and pathologic findings.Results Of the 6 cases,one lesion was located in the frontal lobe,2 in the temporal lobe,1 in the parietal lobe,1 in the posterior fossa and 1 in the fourth ventricle.There was no edema around the lesion.CT findings revealed the calcification as shell-like in 1 case,spot-like in 4 cases and bending strip in 1 case.Calcification located in the center of lesion in 1 case and located in the edge of lesion in 5 cases.On enhanced images,4 cases presented mild to moderate ring-like enhancement in the edge of lesions,and 2 cases showed no enhancement.Pathological findings of 6 cases were epidermoid cysts with granuloma and calcification.Conclu-sion Intracranial calcified epidermoid cyst was rare.Most of the lesions were combined with infection on the pathology findings and enhanced on enhanced images.A careful analysis of the imaging features can help to improve the preoperative diagnosis.