脑动静脉畸形与血流动力性动脉瘤相关性研究

Statistical study on correlation between cerebral arteriovenous malformation and hemodynamic aneurysms

目的 探索与血流动力性动脉瘤有统计学相关性的脑动静脉畸形（AVM）特征性因素.方法 对1999年8月至2009年7月363例AVM患者的资料进行回顾性统计分析;其中男性229例,女性137例,年龄5～65岁,平均（28±13）岁.采用SPSS 16.0统计软件对AVM的13个特征性因素与合并血流动力性动脉瘤之间进行单因素与多因素的相关性分析,对筛选出的因素进行评估.结果 单因素分析表明：与血流动力性动脉瘤存在统计学相关性的因素为发病年龄、部位（幕上、幕下）、AVM的大小、主干供血动脉根数、引流静脉根数、引流静脉扩张、对侧供血、前后循环同时供血.多因素分析表明：发病年龄、主干供血动脉根数、对侧供血与血流动力性动脉瘤存在统计学意义的正相关性,引流静脉根数与血流动力性动脉瘤存在统计学意义的负相关性.结论 与血流动力性动脉瘤相关的AVM特征性因素为发病年龄、主干供血动脉根数、引流静脉根数、对侧供血.

Objective To explore the characteristic factors of arteriovenous malformation （AVM） which have statistically significant correlation with hemodynamic aneurysms. Methods From August 1999 to July 2009, the clinical and imaging indices of 363 consecutive patients with AVM were retrospectively reviewed and entirely statistically analyzed. There were 229 male patients and 137 female patients,the mean age at the time of presentation was 28 ± 13 years. By using SPSS 16. 0 medical statistic software, the correlation were analyzed between hemodynamic aneurysms and 13 characteristic factors associated with AVM through the methods of unit-factor and multi-factor analysis. Finally, the risk of the correlative factors filtrated were evaluated. Results The crosstabs analysis of unit-factor strongly suggested that the following factors,including age, location （supertentorium, subtentorium）, size, number of main feeding arteries, number of drainage veins, ectasis of drainage veins, contralateral supply, and supply by both anterior and posterior circulation, were correlated with hemodynamic aneurysms. And the results of regression analysis of multifactors indicated the following factors, including age, number of main feeding arteries, and contralateral supply, were positively correlated with hemodynamic aneurysms and the number of drainage veins were negatively correlated with hemodynamic aneurysms. Conclusion The factors including age, number of main feeding arteries, number of drainage veins and contralateral supply, are highly correlated with hemodynamic aneurysms.