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磷酸腺苷活化蛋白激酶在内毒素血症大鼠胆固醇水平调节中的作用

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摘要 内毒素血症是现代临床危重病医学面临的棘手问题，也是导致危重症的常见原因和对预后产生严重影响的重要因素，内毒素血症患者往往因为严重感染和应激，处于一个高分解、高消耗的状态。这种能量消耗增加的高分解代谢状态和对代谢底物利用的改变共同构成了此类患者的代谢特征，尤其以高血脂、高血糖、高胆固醇血症为主要特征。磷酸腺苷活化的蛋白激酶（AMPK）可以通过磷酸化HMGR的ser871位点，
作者 徐觅 郑霞 乔巧华 方强
机构地区 浙江大学医学院附属第一医院重症监护室
出处 《中华急诊医学杂志》 CAS CSCD 北大核心 2010年第10期1059-1061,共3页 Chinese Journal of Emergency Medicine
关键词 活化蛋白激酶 高胆固醇血症 内毒素血症 磷酸腺苷 水平调节 大鼠 代谢状态 危重病医学
分类号 R459.7 [医药卫生—急诊医学]
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参考文献11

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中华急诊医学杂志
2010年 第10期

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