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帕罗西汀降低结肠黏膜低度炎症大鼠的内脏敏感性 被引量:5

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摘要 肠易激综合征(irritable bowel syndrome,IBS)是一种以腹部不适和(或)疼痛伴排便习惯改变为特征的功能性肠病,是临床常见疾病之一,其发病机制还未完全明确。精神心理因素、胃肠动力的改变、内脏敏感性的增高等被认为是其重要的病理生理改变。近来学者注意到肠道感染或炎症可能参与IBS发生,炎症可能导致IBS的内脏高敏感性,且认为即使肠道短暂性的轻微炎症都可能激发内脏高敏感性。
出处 《中华消化杂志》 CAS CSCD 北大核心 2010年第10期764-766,共3页 Chinese Journal of Digestion
基金 福建省自然科学基金资助(2009J01138)
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