护卵汤治疗心肾不交型卵巢早衰的临床观察

Clinical study of Huluan decoction on premature ovarian failure of heart-kidney imbalance

目的对护卵汤治疗心肾不交型卵巢早衰的临床疗效进行评价。方法采用随机、阳性药物对照方法,收集病例治疗组30例,对照组30例。治疗组予以护卵汤治疗,对照组采用妈富隆人工周期替代疗法(HRT)治疗,观测2组治疗前后疗效比较、症状评分、血清激素水平(FSH、LH、E2)变化。结果 2组患者治疗前后症状评分、血清激素水平均有显著性变化(P<0.05),中医证侯积分比较治疗组优于对照组(P<0.05),总有效率分别为86.67%和70.00%,两组比较差异有统计学意义(P<0.05)。结论护卵汤对肾虚精亏心肾不交型卵巢早衰患者的血清激素水平和主要症状均有显著改善作用,在改善患者症状方面比对照组更具优势,且治愈率更高,疗效更稳定。

Objective To evaluate the clinical efficacy of Huluan decoction for premature ovarian failure of heart-kidney imbalance.Method Sixty patients were randomly divided into treatment group treated with Huluan decoction and control group treated with HRT;and the changes of two group＇s symptom score and serum hormone levels were measured.Result The symptom score,serum hormone levels of the patients in two groups before and after treatment were significant changes（P0.05）,the integrals of TCM syndrome in treatment group was better than that in control group（P0.05）,and the total effective rate in treatment group was 86.67% and in control group 70.00%（P0.05）.Conclusion Huluan decoction is effective to improve the level of sserum hormones and main symptoms for premature ovarian failure of heart-kidney imbalance,and it has more superiority and higher curative effect in improving symptoms.