长沙市儿童幽门螺杆菌感染情况调查及相关因素分析

Survey and analysis of related factors of helicobacter pylori infections in children in Changsha

目的了解长沙市儿童幽门螺杆菌(helicobacter pylori,Hp)感染的现状及相关因素分析,从而为进一步做好预防工作提供科学依据。方法随机选取长沙市1890名0～15岁儿童进行Hp血清学感染状况调查,并对所有研究对象采取问卷调查了解Hp感染的相关因素。结果长沙市0～15岁儿童Hp感染率为20.4%,其中男、女分别为18.4%和21.9%。Hp感染率总体趋势随年龄增长而增长,但不均衡,以13～15岁感染率最高,随着家庭经济收入的增加,Hp感染率有下降趋势,但在家庭收入最高组,Hp感染率再次升高。父母有胃十二指肠溃疡史的儿童Hp感染率明显高于父母无胃十二指肠溃疡史者,差别有统计学意义。结论长沙市0～15岁儿童感染率处于中等水平,Hp感染与年龄、家庭经济收入、家族胃十二指肠溃疡有关,随年龄增长、家庭经济收入降低,Hp感染率总体趋势呈不规律升高,Hp感染有家族聚集现象。

【Objectives】To learn the status and analyze the related factors of helicobacter pylori infections in children in Changsha,and provide theory basis for prevention.【Methods】1890 0 to 5-year-old children were randomly selected to make seroepidemiological investigation on helicobacter pylori infections,and questionnaire was used to understand the related factors【.Results】Helicobacter pylori infection rate for children aged 0～15 in Changsha was 20.4%,the percentages of infection for male and female were 18.4% and 21.9%,respectively.There has an irregular increasing trend of helicobacter pylori infection rate with the increasing of age,and the age group 13～15 years showed the highest infection rate.However,the infection rate of helicobacter pylori is decreased with the increasing of family income,but the rate was increasing in highest family income group.Hp infection rate of children whose parents have a history of gastric ulcer was significantly higher than children whose parents without a history of gastric ulcer.There have statistical differences.【Conclusions】Helicobacter pylori infection rates for children aged 0～15 in Changsha at the middle level,and Hp infection correlated to age,family income,family gastric ulcer.Helicobacter pylori infection was irregular increasing with the increasing of age and the decreasing of family income.Familial aggregation of Helicobacter pylori infection was shown in this study.