氧化应激在动脉粥样硬化中的作用及研究现状
被引量:3
摘要
心血管疾病的发病率和死亡率逐年上升,动脉粥样硬化(Atherosclerosis,AS)是主要的病理基础。AS是多因素所致病变,主要有血管内皮功能障碍、炎症、氧化应激[1]等。其中氧化应激被认为是AS发生的重要机制之一,本文对氧化应激在AS中的作用及研究现状作一简要综述。
出处
《泸州医学院学报》
2010年第6期710-712,共3页
Journal of Luzhou Medical College
参考文献25
-
1乔晨晖,张凯伦,夏家红.Influence of Oxidized Low Density Lipoprotein on the Proliferation of Human Artery Smooth Muscle Cells in vitro[J].Journal of Huazhong University of Science and Technology(Medical Sciences),2007,27(1):20-23. 被引量:5
-
2Alexandre DT,,Costa SV,Pierre M V.cGM P signalling inpre-and post-conditioning:the role of mitochondria. Cardiovascular Research . 2008
-
3Cathcart MK.Regulation of superoxide anion productionby NADPH oxides in monocytes/macrophages:contribu-tion to atherosclerosis. Arteriosclerosis and Thrombosis . 2004
-
4Xi H,,Akishita M,Nagai K,et al.Potent free radical scav-enger,edaravone,suppresses oxidative stress-induced en-dothelial damage and early atherosc1erosis. Atherosclerosis . 2007
-
5Raij L,DeMaster EG,Jairnes EA,et al.Cigarette smoke-induced,endothelium dysfunction:role of supetoxide an-ion. Journal of Hypertension . 2001
-
6Ballinger S,,Patterson C,Knight-Lozano CA,et al.Mito-chon drial integrity and function in atherogenesis. Circulation . 2002
-
7Jia G,Cheng G,Agrawal DK.Autophagy of vascularsmooth muscle cells in atherosclerotic lesions. Au-tophagy . 2007
-
8Sotnikova R.Investigation of the mechanisms underlyingH2O2-evoked contraction in the isolated rat aorta. GenPharmacol . 1998
-
9Yamaguchi Y,Kunitomo M,Haginaka J.Role of en-dothelial dysfunction in atherosclerosis. Circulation . 2004
-
10Stocker R,Keaney JF Jr.Role of oxidative modifications in atherosclerosis. Physiological Reviews . 2004
二级参考文献10
-
1Nigris F,Youssef T,Ciafre S et al.Evidence for oxida- tive activation of c-Myc-dependent nuclear signaling in human coronary smooth muscle cells and in early lesions of Watanabe heritable hyperlipidemic rabbits: protective effects of vitamin E[].Circulation.2000
-
2Steinberg D,Parthasarathy S,Carew T E et al.Beyond cholesterol Modifications of low-density lipoprotein that increase its atherogenicity[].N Enge J Med.1989
-
3Bachem M G,Wendelin D,Schneiderhan W et al.De- pending on their concentration oxidized low density lipo- proteins stimulate extracellular matrix synthesis or induce apoptosis in human coronary artery smooth muscle cells[].Clinical Chemistry and Laboratory Medicine.1999
-
4Argmann C A,Sawyez C G,Li S et al.Human smooth muscle cell subpopulations differentially accumulate cholesteryl ester when exposed to native and oxidized lipoproteins[].Arteriosclerosis and Thrombosis.2004
-
5Vries C J,Achterberg T A,Horrevoets A J et al.Differ- ential display identification of 40 genes with altered ex- pression in activated human smooth muscle cells Local expression in atherosclerotic lesions of smags, smooth muscle activation-specific genes[].Journal of Biological Chemistry.2000
-
6Mata P,Varela O,Alonso R et al.Monounsaturated and polyunsaturated n-6 fatty acid-enriched diets modify LDL oxidation and decrease human coronary smooth muscle cell DNA synthesis[].Arteriosclerosis and Thrombosis.1997
-
7Wells K E,Miguel R,Alexander J J et al.Transmem- brane calcium flux regulates LDL oxidation by arterial smooth muscle cells[].Journal of Surgical Research.1997
-
8Steinbrecher U P,Zhang H F,Lougheed M.Role of oxi- datively modified LDL in atherosclerosis[].Free Radical Biology and Medicine.1990
-
9Norata G D,Tonti L,Roma P et al.Apoptosis and prolif- eration of endothelial cells in early atherosclerotic lesions: possible role of oxidised LDL[].Nutr Metab Cardiovasc Dis.2002
-
10Norata G D,Tonti L,Roma P et al.Apoptosis and prolif- eration of endothelial cells in early atherosclerotic lesions: possible role of oxidised LDL[].Nutr Metab Cardiovasc Dis.2002
共引文献4
-
1汪莲开.氧化应激致动脉粥样硬化的研究进展[J].湖北民族学院学报(医学版),2008,25(1):49-52. 被引量:6
-
2王世祥,吴宏超,季爱民,孙靓,杜英,车瓯,张培东.自制α-硫辛酸缓释片对氧化低密度脂蛋白致兔实验性动脉粥样硬化的影响[J].中国组织工程研究与临床康复,2009,13(3):483-486.
-
3龚福明,柳陈坚.传统大豆发酵食品在心脑血管疾病防治上的研究现状[J].中国微生态学杂志,2009,21(4):369-373. 被引量:3
-
4盛臻强,黎叶飞,卢辉和.吡格列酮的抗氧化作用对代谢综合征患者血管内皮细胞功能的影响[J].南通大学学报(医学版),2012,32(3):191-193. 被引量:1
同被引文献36
-
1周慧君,杨积武.氧自由基与冠心病及其中医药研究[J].辽宁中医学院学报,1999,1(2):139-141. 被引量:16
-
2王旋,顾振纶,秦振红,张慧灵.银杏内酯A和B混合物对大鼠永久性局灶性脑缺血的保护作用[J].中草药,2007,38(2):241-244. 被引量:27
-
3O' Neill T J, Wamhoff B R, Owens G K, et al. Mobilization of bone marrow-derived cells enhances the angiogenic response to hypoxia without transdifferentiation into endothelial cells [ J ]. Circ Res, 2005, 97(10) : 1027-1035.
-
4Zentilin L, Tafuro S, Zacchigna S, et al. Bone marrow mono- nuclear cells are recruited to the sites of VEGF - induced neo- vascularization but are not incorporated into the newly formed vessels[J]. Blood, 2006, 107(9): 3546-3554.
-
5Migdal C, Serres M. Reactive oxygen species and oxidative stress [J]. Med Sci(Paris) ,2011,27 (4) :405-412.
-
6Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease [J]. Am J Cardiol, 1983,51(3) :606.
-
7Tousoulis D, Psahopoulou T,Androulakis E, et al. Oxidative stress and early atherosclerosis: novel antioxidant treat-ment [J]. Cardiovasc Drugs Ther,2015, 29( 1 ) : 75-88.
-
8Lushchak VI. Free radicals, reactive oxygen species, oxidative stress and its classification [J]. Chem Biol Interact, 2014,224(C) : 164-175.
-
9周凯章,林辉丽.血红素氧化酶-1对小鼠动脉粥样硬化斑块抑制作用的研究[J].福建医药杂志,2008,30(1):89-90. 被引量:1
-
10周晓峰,王佐.内皮祖细胞在动脉粥样硬化进程中的作用[J].中国动脉硬化杂志,2007,15(12):940-942. 被引量:22
引证文献3
-
1焦鹏,杨娜娜,崔英杰,秦树存.泰山白花丹参提取物体外对氧化应激损伤内皮祖细胞作用的研究[J].中成药,2013,35(12):2730-2732. 被引量:6
-
2叶胜,汤圣兴.氧化应激对不同类型冠心病的影响及其因素分析[J].实用医学杂志,2015,31(24):4151-4152. 被引量:4
-
3俞建,胡文志.银杏酮酯分散片对冠心病稳定性心绞痛氧化应激的影响[J].天津中医药,2017,34(2):103-105. 被引量:16
二级引证文献26
-
1韩琳娜,李一梅,谢波.复方丹参滴丸治疗非增生期糖尿病视网膜病变的研究进展[J].中成药,2015,37(2):382-384. 被引量:25
-
2张光银,马惠宁,李南南,曹阳,张军平.补肾抗衰片对乳兔来源内皮细胞HO-1相关氧化应激水平的影响[J].中华中医药杂志,2017,32(4):1840-1843. 被引量:1
-
3赵俊坡.健脾利湿方对代谢综合征患者炎症因子水平及氧化应激的影响[J].河北中医,2016,38(5):666-670. 被引量:6
-
4章激,田艳,薛瑞.参麦注射液体外诱导骨肉瘤MG-63细胞凋亡的机制研究[J].中医药导报,2016,22(22):28-31. 被引量:3
-
5俞建,钱琦.稳定性心绞痛患者SIRT1表达与氧化应激的相关性研究[J].南京医科大学学报(自然科学版),2017,37(5):637-638. 被引量:9
-
6石永强,漆军华,宋用强,张敦福,张力.根除幽门螺旋杆菌对冠心病患者血清氧化应激状态及预后因素的影响[J].吉林医学,2017,38(7):1252-1253. 被引量:1
-
7宋媛,都雯,马蕾,王旭敏,赵先彬,齐玲.银杏黄酮苷与复方丹参片对冠心病心绞痛患者心电图、心功能、血液流变学的影响对比分析[J].世界中医药,2017,12(8):1764-1766. 被引量:15
-
8李毅,李斌,曾伟,颜安明,王军,秦逸辉,余妍,吴志峰.滋心阴胶囊联合西药治疗冠心病心绞痛患者的机理探讨[J].河北医学,2017,23(9):1528-1531. 被引量:4
-
9吕国伟.阿托伐他汀联合曲美他嗪治疗冠心病稳定性心绞痛效果分析[J].河南医学研究,2018,27(11):2057-2058. 被引量:5
-
10岑运光,李伟,张旭日,吴多智.银杏叶注射液对老年高血压冠心病患者内皮素及冠脉血流的影响[J].中华中医药学刊,2018,36(11):2754-2756. 被引量:15
-
1陈宝峰,徐新.体外反搏改善冠心病患者血管内皮功能的研究进展[J].心血管病学进展,2006,27(6):760-763. 被引量:4
-
2喇素荣.氟伐他汀治疗慢性充血性心力衰竭的效果观察[J].宁夏医科大学学报,2015,37(3):330-332. 被引量:4
-
3牛峰海.血管内皮功能障碍与心血管疾病[J].医学综述,1999,5(7):321-323.
-
4赵洪林,张丽彤,张卿,焦焕利,宋崑,李研凭.代谢综合征患者动脉僵硬度与相关危险因素的研究[J].中华健康管理学杂志,2010,4(3):178-179.
-
5杨丕坚,吕以培,李舒敏.血管内皮功能障碍与2型糖尿病相关性研究进展[J].中华实用诊断与治疗杂志,2014,28(6):532-534. 被引量:11
-
6韩华峰,周东华.阿托伐他汀治疗原发性高血压的疗效及对C-反应蛋白水平的影响[J].社区医学杂志,2011,9(6):76-78. 被引量:3
-
7陶军,杨震.代谢综合征与内皮功能障碍[J].新医学,2009,40(11):756-758. 被引量:4
-
8周少春.血管内皮功能障碍的早期检测及对策[J].岭南心血管病杂志,1998,4(1):62-64. 被引量:6
-
9于涛,丛武,张惠军.C反应蛋白与不稳定型心绞痛危险分层的关系[J].中国社区医师(医学专业),2004,6(22):68-69.
-
10高明献,高开亮,饶建良.缺血预适应对急性心肌梗死QT离散度的影响[J].江苏实用心电学杂志,1999,20(4):230-230.