灯盏花素注射液治疗不稳定型心绞痛的疗效和安全性观察

Effective and security observation on treating unstable angina with Breviscapine injection

目的：评价灯盏花素注射液治疗不稳定型心绞痛（Unstable angina,UA）的疗效.方法：80例UA患者,分成观察组和对照组.对照组：硝酸酯类药物、β受体阻滞剂、阿司匹林、ACEI及降脂药物等常规治疗;观察组：在对照组常规治疗方法的基础上,加用灯盏花素注射液.结果：两组心绞痛疗效比较：差异均无统计学意义（P〉0.05）.两组心电图疗效比较：观察组总有效率优于对照组,差异具有显著性（P〈0.05）.两组中医证候疗效比较：观察组总有效率优于对照组,差异具有显著性（P〈0.01）.两组均未见明显的不良反应.结论：在硝酸酯类药物、β受体阻滞剂,阿司匹林等常规治疗基础上,加用灯盏花素注射液治疗UA患者,疗效可靠,副作用也较小.

Objective： To evaluate the effective of treating unstable angina with Breviscapine injection （Unstable angina, UA）. Methods： 80 patients with UA were divided into observation group and control group. Control group： nitrates, 13 blockers, aspirin, ACEI and lipid-lowering drugs and other conventional treatment; observation group： in the control group on the basis of conventional treatment, plus breviscapine. Results： Angina comparison： the difference was not statistically significant （P〉0.05）. Compared with two groups ECG effect： observation groups was batter than control group, has a significant difference （P〈0.05）. Compared with two groups effective of TCM： observation groups was batter than control group, has a significant difference （P〈0.01）. Two groups weren＇t adverse reactions. Conclusion： Treating UA by basis therapy of nitrates, 13 blockers, aspirin, ACEI and lipid-lowering drugs plus breviscapine injection has a good effects, fewer side effects.