血透患者皮下注射促红素局部压迫时间与皮下出血关系的探讨

Approach of Relationship of Erythropoietin Subcutaneously Local Compression Time and Subcutaneous leeding

目的:探讨促红素皮下注射局部压迫时间与皮下出血发生率及出血面积关系,同时找出最短的较有效的压迫时间,以减少皮下出血的发生率,减小出血面积。方法:选择尿毒症维持性血透患(?)将每例患者的10次皮下注射随机分为5组,每组压迫时间为:1min,2min,3min,4min,5min,观察皮下出血的次数(?)出血面积的大小。结果:促红素皮下注射局部不同压迫时间与皮下出血存在统计学差异,P<0.01,且4 min组与3 min组出血率比较,差异具有统计学意义,P<0.01,而其他相邻组间无统计学差异;局部不同压迫时间与出血面积存在统计学差异,P<0.05,且较大面积(>2cm×2cm)出血率在4min组与3min组之间有统计学差异,P<0.05,而其他相邻组间无统计学差异。结论:局部压迫4min可以有效降低局部出血发生率和减小较大面积出血。

Objective：To investigate erythropoietin subcutaneously local compression time and the incidence of subcutaneous bleeding and bleeding - area relationship,and find the shortest possible time for a more effective repression in order to reduce the incidence of subcutaneous bleeding and reduce the bleeding area.Methods：uremic hemodialysis patients,each of the 10 patients were randomly divided into five subcutaneous injection groups,each of oppression time;1min,2min,3min, 4min,5min,observe the frequency of subcutaneous bleeding and bleeding area size.Results：Erythropoietin in different subcutaneous partial pressure of subcutaneous bleeding time and there is significant difference,P0.01,and 4 min groups compared with the bleeding rate 3min group,the difference was statistically significant,P0.01,while the other adjacent groups no statistical difference;local time and bleeding in different areas of oppression there is significant difference,P0.05,and a large area（2cm×2cm） bleeding rate of 4 min group and 3min statistically significant difference between groups,P0.05,while the other was no significant difference between adjacent groups.Conclusion：Local compression 4min can effectively reduce the incidence and reduce local hemorrhage larger bleeding.