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卡培他滨联合多西紫杉醇节拍化疗治疗转移性乳腺癌25例临床护理 被引量:2

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摘要 目的:观察卡培他滨联合多西紫杉醇节拍化疗治疗转移性乳腺癌(MBC)的疗效、不良反应,探讨其护理方法。方法:25例患者给予卡培他滨采用500 mg,3次/d,连续口服第1~14 d;国产多西紫杉醇25 mg/m2,静脉滴注持续1 h,第1、8天给药;每21 d重复。针对化疗出现的不良反应进行针对性护理。结果:25例中CR 2例,PR 12例,SD6例,PD 5例,RR为56%(14/25),DCR为80%(20/25)。不良反应为Ⅰ~Ⅱ度白细胞下降、关节肌肉酸痛及手足综合征、消化道反应,Ⅲ度不良反应少见,无Ⅳ度不良反应。结论:卡培他滨联合多西紫杉醇节拍化疗治疗MBC,具有疗效好、副作用小及患者依从性好等优点。
作者 姜佳 张慧玲
机构地区 解放军第
出处 《齐鲁护理杂志》 2010年第11期30-31,共2页 Journal of Qilu Nursing
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