摘要
以单向矩形波脉冲(脉宽0.5～1ms,频率40～70Hz,电流强度100～300μa,A)刺激麻醉家兔下丘脑乳头体核及其周围区域,可以诱发以期前收缩为主要特征的心律失常和动脉血压明显升高。维持兔动脉血压处于不同水平。当动脉血压在较高水平时,刺激下丘脑乳头体区域所诱发的期前收缩明显增多;当动脉血压处于较低水平时,刺激所诱发的期前收缩显著减少,动脉血压的高低与刺激所诱发的心律失常之间有显著的正相关关系。
In ansethetized rabbits arrhythmia (mainly ecotopic deats) and striking ele- vation of arterial blood pressure could be elicited during and after stimulation of mamillary nucleus of the hypothalamus and its surrounding regions by monophasic square wave trains lasted 5~10 seconds (pulse duraion: 0.5~1ms; frequency: 40~70Hz; current intensity: 100~300μA). when blood pressure was at higher levels, stimulation of hypothalamus could elicit an increased response of arrhythmia. when blood pressure was at lower levels, stimulation of hypothalamus could elicit a decreased response of arrhythmia The results showed that there was significant correlation between levels of blood pressure and arrhythmia induced by stmulation of hypothalamus.
关键词
下丘脑
乳头体核
心律失常
电刺激
hypothalamus
mamillary nucleus
arrhythmia
arterial blood pressure
