肺脏复发性血栓栓塞症的病理学研究

The Pathological Research of the Recurrent Pulmonary Thromboembolism

肺脏复发性血栓栓塞症是一种少见的疾病,早期常不产生明显的临床症状,晚期则多表现为肺源性心脏病。作者对8例肺脏复发性血栓栓塞症病人的肺脏进行了全面的病理学检查,综合出其病变特点为:分布极为普遍,两肺任一肺段的血管均能发现不同程度的病变;主要见于动脉系统,各种口径的血管均可受侵犯,但以肺脏的大中型动脉为主;血栓有明显的机化倾向。

Recurrent pulmonary thromboembolism is a rare disease. There is no prom- inent symptom in its early stage, but in the later period cot pulmnale can be found. The main changes in this disease are recurrent thrombosis and thrombus organization in the pulmonary artery, therefore, it can lead to different vascu- lar obstruction. The resistence of pulmnary circulation increases following the severity of obstruction, cor pulmonale can occur and finally leading to death of the patient. Sometimes, acute embolism of a larger pulmonary artery can also be lethal. This article has summarized the pathological characteristics of the recurrent pulmonary thromboembolism after searching three patients. It shows that the damages mainly occur in the arterial system, especially large and medial arteries, and the thrombus is apt to produce organization and reca- nalization.