HBsAg阳性的胃溃疡患者HCV感染的情况分析

Analysis of HCV infection in HBsAg - positive patients with gastric Ulcer

为探讨ＨＢｓＡｇ阳性的胃溃疡患者ＨＣＶ感染情况。方法用ＥＬＩＳＡ法及ＰＣＲ法对ＨＢｓＡｇ阳性的胃溃疡患者７５例（其中接受输血者３８例，未输血者３７例）和单纯ＨＢｓＡｇ阳性患者３２例的血清进行抗－ＨＣＶ和ＨＣＶＲＮＡ测定。结果接受输血者抗－ＨＣＶ及ＨＣＶＲＮＡ阳性率明显高于未输血者及单纯ＨＢｓＡｇ阳性患者（Ｐ＜０．０１）。结论输血为传播ＨＣＶ的主要途径，未发现消化道传播ＨＣＶ的证据。

Aim To observe the infeCtion of hepatitis C virus (HCV) in HBsAg-Positive patients with gastric ulcer.Methods The antibody to hepatitis C vims was detected in sera from 75 HBsAg-Positive Patients with gastric ulcer (38 received blood transfusion, 37 did not) and 32 HBsAg-Positive individuals, using second generation enzyme-linked immunosorbentassay (EllSA). Sera from all cases were aam detected with polymemee chain reactionn (PCR) to detect HCVRNA. ResultsThe Positive the of anti - HCV and HCVRNA in HBsAg-positive Patients with gastric ulcer who had received blood transfusionwas higher than that of HBsAg-POsitive patients with gastric ulcer who did not receive blood transfusion and HBsAg-Positive individuals. Conclusion Transfusion is a major factor of HCV infection. No evidences evidences found that HCV is transmitted boughdigestive tract.