期刊文献+

脑梗死患者蛋白质Z检测的临床意义 被引量:3

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摘要 目的方法采用双抗体夹心ELISA法检测75例急性脑梗死患者不同时间点血浆蛋白质Z水平,依据梗死灶面积大小分为轻度、中度及重度梗死组,另择50例健康体检者作为对照组,比较各组的血浆蛋白质Z水平。结果梗死组血浆蛋白质Z水平明显低于对照组(P<0.01);入院时、治疗7 d及14 d梗死组与对照组比较均有统计学差异(P均<0.01);重度梗死组明显低于中度及轻度梗死组,中度梗死组明显低于轻度梗死组(P均<0.01)。结论血浆蛋白质Z参与了脑梗死的发病过程,并与梗死严重程度密切相关,可能是急性脑梗死早期预警因子之一。
作者 孔岳南 孙杨
出处 《山东医药》 CAS 北大核心 2010年第49期61-62,共2页 Shandong Medical Journal
基金 无锡市社会发展计划资助项目(CSZ00705)
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参考文献5

  • 1孙杨,孔岳南,文芳.血栓性疾病患者蛋白质Z含量的研究[J].中国综合临床,2008,24(10):1012-1013. 被引量:2
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二级参考文献28

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共引文献3

同被引文献20

  • 1Michiels JJ. Low portein Z associated with venous thrombophilia and with ischemic stroke [ J]. Seminars in Vascular Medicine, 2002,2 (2) :121-123.
  • 2孙杨,孔岳南,文芳.蛋白Z与卒中[J].国际脑血管病杂志,2007,15(10):797-800. 被引量:4
  • 3Sun Y,Wen F,Yao Hy. Protein Z and ischemic stroke[J].Vascular Disease Prevention,2005,(03):245-250.
  • 4Tran HA,Eikelboom JW. Role of protein z in stroke[J].Current Treatment Options in Cardiovascular Medicine,2007,(03):191-197.
  • 5Koren-Michowitz M. Protein Z and its role in venous and arterial thrombosis[J].IMAJ,2006,(01):53-55.
  • 6Kobelt K,Biasiutti FD,Heinrich P. Protein Z in ischemic stroke[J].Blood J Haemalogy,2001,(01):169-173.
  • 7Vasse M,Guegan-Massardier E,Borg JY. High frequency of protein Z deficiency in patients with ischemic stroke[J].The Lancet,2001,(9260):933-934.
  • 8Heeb MJ. Association of low protein Z levels with ischemic stroke in young women[J].Thrombosis and Haemostasis,2007,(03):495-496.
  • 9Fatima S. Al-Shaikh,Mai S. Sater,Ramzi R. Finan,Eddie Racoubian,Tala M. Abu-Hijleh,Fekria E. Mustafa,Wassim Y. Almawi.Protein Z Variants Associated With Protein Z Plasma Levels and With Risk of Idiopathic Recurrent Miscarriage[J]. Reproductive Sciences . 2013 (9)
  • 10Georgios Tsivgoulis,Sofia Vassilopoulou,Konstantinos Spengos.Potential applicability of ABCD 2 score in triaging TIA patients[J]. The Lancet . 2007 (9567)

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