期刊文献+

血浆B型钠利尿肽水平与冠脉病变程度的关系 被引量:5

下载PDF
导出
摘要 目的探讨血浆B型钠利尿肽(BNP)水平与冠脉病变程度的关系。方法根据123例冠心病(CHD)及可疑CHD患者的冠脉造影结果进行Gensini评分,其中A组20例(Gemini评分0分),B组20例(Gensini评分1—20分),C组49例(Gensini评分21—40分),D组34例(Gensini评分〉40分);均于入院后24h内检测血浆BNP,比较四组血浆BNP水平,分析血浆BNP水平与Gensini积分的相关性。结果四组血浆BNP水平经Lg(BNP)转换后,B、C、D组Lg(BNP)均明显高于A组,C、D组明显高于B组,D组明显高于C组(P〈0.05或〈0.01);血浆BNP水平与Gemini积分呈明显正相关(ra=0.849,P〈0.01)。结论CHD患者的血浆BNP水平明显高于正常,其血浆BNP水平与Gensini积分呈明显正相关;血浆BNP水平能反映冠脉病变程度,为CHD患者的独立危险因素。
出处 《山东医药》 CAS 北大核心 2010年第49期74-75,共2页 Shandong Medical Journal
  • 相关文献

参考文献6

  • 1Gensini GG.A more meaningful scoring system for determining the severity of coronary heart disease[J].Am J Cardiol,1983,51(3):606-607.
  • 2Hara Y,Hamada M,Shigematsu Y,et al.Effect of beta-bloeker on left ventricular funetion and natriuretic peptides in patients with chronic heart failure treated with angiotensin-converting enzyme inhibitor[J].Jpn Circ J,2000,64(5):365-369.
  • 3Nicholls MG,Lainchbury JG,Riehards AM,et al.Brain natriuretic peptide guided therapy for heart failure[J].Ann Med,2001,33(6):422-427.
  • 4Clerico A,Iervasi G,Mariani G.Pathophysiologic relevance of measuring the plasma levels of cardiac natriuretic peptide hormones in humans[J].Horm Metab Res,1999,31(9):487-498.
  • 5Maeda K,Tsutamoto T,Wada A,et al.Plasma brain natriuretic peptide as a bioehemical marker of high left ventrieular end-diastolic pressure in patients with symptomatic left ventricular dysfunetion[J].Am Heart J,1998,135(5):825-832.
  • 6Marurnoto K,Hamada M,Hiwada K,et al.Increased secretion of atrial and brain natriureitc peptides during acute myocardial ischemia induced by dynamic exercise in patients with angina pectoris[J].Clin Sci,1995,88(5):551-556.

同被引文献67

二级引证文献34

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部