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氨基末端脑钠肽前体在心力衰竭检测中的临床意义 被引量:1

Study of Serum Nt-ProBNP Level in Patients with Congestive Heart Failure
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摘要 目的:探讨充血性心力衰竭患者血浆氨基末端脑钠肽前体(NT-proBNP)水平的变化。方法:应用电化学发光免疫分析仪测定健康人组80例和心力衰竭组80例(心功能Ⅱ级25例、Ⅲ级30例、Ⅳ级25例)血清NT-proBNP的水平。结果:心力衰竭组NT-proBNP水平较健康组明显增高,且随心功能的恶化NT-proBNP水平增高。结论:充血性心力衰竭患者血清NT-proBNP水平明显增加,且随着心功能分级程度的加重而显著增加。 Objective:To study the relation between the level of NT-proBNP in patients with congestive heart failure and the person with normal heart function.Methods:The study subjects were divided into two groups:normal heart function group and congestive heart failure(CHF)group,The NT-proBNP was detected by electrochemistry luminescence method.Results:The level of NT-proBNP in patients with congestive heart failure were higher than that in normal heart function group(P〈0.05) and declined with cardiac function improvement(P〈0.05).Conclusion:The level of NT-proBNP has a relation with cardiac function and it may be a good prediction in diagnosing CHF and evaluating cardiac function.
作者 沈军瑾
机构地区 江西省肿瘤医院
出处 《实用中西医结合临床》 2010年第5期72-73,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
关键词 心力衰竭 充血性 NT-PROBNP Heart failure Congestive NT-proBNP
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  • 1Bozkurt B,Mann DL. Use of biomarkers in the management of heart failure: are we there yet[J].Circulation, 2003,107:1 231-1 233.
  • 2Silver MA.The natriuretic peptide system: kidney and cardiovascular effects[J]. Curr Opin Nephrol Hypertens,2006,15( 1 ): 14-21.
  • 3王瑶,陶则伟,陆贤,黄元伟.B型钠尿肽的研究进展[J].心脏杂志,2003,15(6):555-557. 被引量:41

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