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补气通络解毒方对胰腺癌模型小鼠Shh信号通路调节机制的研究 被引量:1

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摘要 目的:研究补气通络解毒方对胰腺癌模型小鼠Shh信号通路的影响。方法:采用移植癌细胞的方法,将24只裸小鼠制作成胰腺癌模型,并随机分为治疗组和对照组,每组12只,治疗组采用补气通络解毒方灌胃。对照组采用生理盐水灌胃;治疗结束后,处死各组小鼠,采用RT-PCR法检测小鼠瘤组织ShhmRNA的表达。结果:治疗组小鼠ShhmRNA表达情况明显低于对照组。结论:补气通络解毒方能阻断Shh信号通路,这也可能是该方治疗胰腺癌的生物学机制之一。
出处 《实用中西医结合临床》 2010年第5期88-89,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
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参考文献7

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