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吸入麻醉药“浓度效应”的定量分析

Quantitative Analysis on the Effects of Concentration
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摘要 目的:对吸入麻醉药的浓度效应做出定量分析。方法:利用热力学的宏观理论和高等数学的思维方法,分三个层面讨论浓度效应:肺泡内麻醉药的浓度与吸入浓度的关系;肺泡内麻醉药的分压与吸入浓度的关系;血液中麻醉药的分压与吸入浓度的关系。结果:吸入浓度越高,肺泡内麻醉药的浓度升高越快,肺泡内麻醉药的分压和血中麻醉药的分压也上升的越快。结论:浓度效应的存在能用数学物理的方法给予证明。 Objective: To make a quantitative analysis on the effects of Concentration.Methods: Physical theory and advanced mathematical thinking was used in quantitative analysis,which showing the relationship among the inhaled anesthetics concentration,the anesthetics partial pressure in alveolar,and the anesthetics partial pressure in blood.Results: Quantitative analysis shows that the inhaled anesthetics with higher concentration can lead to greater anesthetics partial pressure in alveolar.As a result,the anesthetics partial pressure in blood also rises.Conclusion:The effects of anesthetics concentration does exist,and it can be proved by Mathematical and Physical methods.
出处 《数理医药学杂志》 2010年第6期644-647,共4页 Journal of Mathematical Medicine
基金 国家自然科学基金资助项目(30872432 30471657 39970715) 江苏省自然科学基金资助项目(BK2001143) 徐州医学院科研基金资助项目(2010KJ23)
关键词 麻醉药 浓度 分压 定量分析 anesthetics concentration partial pressure
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参考文献5

  • 1Eger EI II.The effect of inspired concentration on the rate of rise of alveolar concentration.Anesthesiology,1963,24:153-157.
  • 2Ronald D.Miller.Anesthesia,5thed,2000,78-79.
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  • 4戴体俊,主编.麻醉药理学.第2版.人民卫生出版社,2006,55.
  • 5张选群.医学高等数学.第4版.人民卫生出版社,2007,40-45.

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