摘要
目的:探讨呋塞米联合酚妥拉明对新生儿呼吸衰竭的疗效。方法:血气分析及X线资料完整的226例新生儿呼吸衰竭患儿随机双盲分成对照组和实验组,实验组在对照组病因治疗和供氧治疗的基础上加用甲磺酸酚妥拉明0.5 mg/kg,1次/6 h,视病情逐渐延长间隔时间,直至停药,同时予小剂量呋塞米0.2 mg/(kg.d)静脉注射。治疗前和治疗24 h后对两组血气分析差值进行比较。结果:治疗24 h后血气分析结果显著改善,两组比较差异均有统计学意义(P<0.01)。结论:呋塞米联合酚妥拉明治疗新生儿呼吸衰竭效果好,针对病情较重的患儿宜及早使用。
Objective:To study the treatment of Furosemide plus Phentolamine on the neonatal respiratory failure.Methods:Two hundred and twenty-six patients were double-blindly randomized into two groups.The control group was treated with regular methods,and the experiment group was given the phentolamine and furosemide.Then the data of blood gas analysis in both groups were statistically analyzed.Results:Changes of blood gas in the experiment group were better than that in the control group(P0.01).Conclusions:It is believed that Phentolamine and Furosemide is necessary and good effect could be expected.
出处
《儿科药学杂志》
CAS
2010年第6期23-24,共2页
Journal of Pediatric Pharmacy
关键词
新生儿
呼吸衰竭
酚妥拉明
呋塞米
Neonatal
Respiratory failure
Phentolamine
Furosemide