摘要
目的:探讨冷水循环型微波(microwave,MW)热疗治疗肝癌的近期疗效及安全性。方法:用FORSEA MTC-3冷水循环型微波肿瘤热疗仪治疗肝癌患者160例,共239个结节,通过影像学检查及随访观察其疗效。结果:MW治疗区增强CT扫描检查示各期均无强化,周边可见很薄的环形强化,治疗的坏死范围要大于治疗前病灶范围。以肝脏增强CT扫描评估单针穿刺消融范围,为长轴4-4.5 cm,横轴3.3-3.5 cm的类椭圆体。肿瘤完全坏死率为84.9%(203个结节)。1年生存率为91.3%(146/160),2年生存率为80.2%(69/86)。MW治疗肝癌并发症少,多为发热、肝功能异常、胸水等,偶见肝脓肿,无一例手术死亡。结论:MW热疗可作为肝癌的一种安全有效的微创治疗方法。
Objective:To evaluate short-term therapeutic efficacy and safety of cooled-tip electrode microwave ablation of liver cancer.Methods:One hundred and six patients(239 nodes) of liver cancer were treated with a new cooled-tip electrode microwave(FORSEA MTC-3).The contrast-enhanced CT and follow-up were used to evaluate the short-term therapeutic efficacy.Results:The ablated area was not enhanced on contrast-enhanced CT,the tissue around ablated area was enhanced.The necrosis area after treatment was larger than tumor size before treatment.The coagulative extent after one application of MW was 4.0-4.5cm in length wise and 3.3-3.5cm in transversal wise according to contrast-enhanced CT.The tumor complete ablation rate was 84.9%(203 nodes).The 1 year survival rate was 91.3%(146/160),and the 2 year survival rate was 80.2%(69/86).There were a few complications occurred such as fever,liver function abnormality,pleural fluid and liver abscess.No patients died during the process.Conclusions:The innovated MV ablation is safe and effective for mini-invasive treatment of liver cancer.
出处
《腹腔镜外科杂志》
2010年第11期811-813,共3页
Journal of Laparoscopic Surgery
关键词
超声疗法
肝肿瘤
微波
Ultrasonic therapy
Liver neoplasms
Microwaves