血清β-HCG和孕酮监测对异位妊娠药物治疗的效果评价

Evaluation of Serum β-Human Chorionic Gonadotropin and Progesterone in Monitoring Ectopic Pregnancy for Medicinal Conservative Treatment

目的:探讨血清β-HCG和孕酮在异位妊娠药物保守治疗中的检测作用。方法:选择已确诊异位妊娠且采取药物治疗成功者48例,监测治疗前后血清绒毛膜促性腺激素(β-HCG)和孕酮值,并统计两者下降至正常值所需时间。结果:治疗前和治疗后第4天血清β-HCG值及孕酮下降幅度相比有明显差异(P<0.01),孕酮下降至正常所需时间显著少于β-HCG下降至正常的时间(P<0.01)。结论:药物治疗异位妊娠过程中,血清孕酮下降幅度显著大于β-HCG,而降至正常时间显著少于β-HCG,孕酮对异位妊娠的药物治疗的检测作用优于β-HCG。

Objective：To investigate the value of β-hunlan chofionic gonadotropin（β -HCG）and progesterone in monitoring ectopic pregnancy for medicinal conservative treatment . Methods： Forty - eight patients with ectopic pregnancy were selected, Serum β - HCG and progesterone were successively mornitored before and ＇after treatment. The time of serum β - HCG and progesterone declining to normal levels was recorded. Results： Compared with the amplitude of decrease of serum β - HCG and progesterone,there were significant differences in curative rate （P 〈 0. 01 ） and compared with the time of serum β- HCG and progesterone declining to normal levels, progesterone level decreased more significantly in the patients with successful treatment （P 〈0.01 ）. Conclusion： During the medicinal conservative treatment for ectopie pregnancy, the amplitude of decrease of serum progesterone is larger and the time of serum progesterone level declining to normal one is shorter than those of β - HCG. Therefore, serum progesterone monitoring is better than β - HCG monitoring.