重视MRI对易损斑块的研究

We must pay special attention to MR imaging for evaluation of vulnerable plaque

研究已表明,易损斑块是导致急性冠脉综合征(ACS)和脑卒中的主要原因。利用简便、准确、无创的诊断技术对易损斑块进行早期检测以及对其致病机制进行研究,是当前心脑血管疾病研究的热点和难点。近年来,随着磁共振软、硬件技术的发展,MRI可以直接观察血管管壁情况,对斑块的大小、体积及斑块成分提供较为准确的信息,广泛应用于动脉粥样硬化斑块的检测和预后评估。本组专题围绕易损斑块的定义和诊断标准、影像学检查方法、MRI检测易损斑块的优势与不足、以及MRI评价易损斑块的临床新进展等内容进行全面系统地阐述,同时,并对MRI检测易损斑块的发展方向及其面临的挑战进行展望。

Studies have suggested that vulnerable plaque is the main cause that leads to acute coronary syndrome（ACS） and stroke.The prevention and treatment of cardio-cerebrovascular disease focuses on the early detection of the vulnerable plaque and its pathogenic mechanism by using noninvasive techniques.During recent years,advanced MR techniques have increasingly been applied to observing the details of the vessel wall including the size,mass,composition of the vulnerable plaque,therefore MRI was widely used for diagnosis and prognosis of the atherosclerotic plaque.In these special reports,the definition and diagnostic criteria of vulnerable plaque,the comparison of different imaging techniques,the advantages and disadvantages of MR imaging,and the status of MRI in clinical evaluation of the vulnerable plaque will be systematically reviewed,meanwhile,the development trend of MR techniques in the detection of vulnerable plaque is also emphasized.