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易损斑块的含义和诊断标准 被引量:8

The definitions and diagnostic criteria of vulnerable plaque
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摘要 易损斑块也被称为高危斑块(high-risk plaque)、危险斑块(dangerous plaque)、不稳定斑块(unstable plaque),以及软斑块、非钙化斑块或AHA Ⅳ型斑块(AHA type Ⅳ plaque)等。2003年Naghavi等根据尸检资料提出了诊断易损斑块的主要标准和次要标准。主要标准包括:①斑块内活动性炎症;②薄纤维帽及大脂质核心;③内皮细胞脱落伴表层血小板聚集;④裂隙斑块与受损斑块;⑤严重狭窄。次要标准包括:①浅表钙化结节;②黄色斑块;③斑块内出血;④内皮功能异常;⑤延展重构(正性重构)。本文详细介绍易损斑块的诊断标准。 Vulnerable plaque was also called high-rish plaque,dangerous plaque,unstable plaque,soft plaque,non-calcified plaque or AHA type IV plaque,etc.In 2003,Naghavi et al established the diagnostic criteria for detection of vulnerable plaque based on the autopsy results,the major criteria included the following features:(1) Active inflammation,(2) A thin cap with a large lipid core,(3) Endothelial denudation with superficial platelet aggregation,(4) Fissured/Injured plaque,(5) Severe stenosis;the minor criteria included(1) Superficial calcified nodules,(2) Yellow color(on angioscopy),(3) Intraplaque hemorrhage,(4) Endothelial dysfunction,(5) Expansive(Positive) remodeling.The article stressed upon reviewing the diagnostic criteria.
作者 赵世华
出处 《磁共振成像》 CAS 2010年第6期408-410,共3页 Chinese Journal of Magnetic Resonance Imaging
关键词 易损斑块 定义 诊断标准 Vulnerable plaque Definition Diagnostic criteria
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参考文献11

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