加替沙星与左氧氟沙星治疗下呼吸道感染的成本-效果分析

Cost-effectiveness analysis of Gatifloxacin and Levofloxacin in the treatment of patients with lower respiratory tract infection

目的评价加替沙星与左氧氟沙星治疗下呼吸道感染的成本-效果,促进合理用药,降低医疗费用。方法利用已有文献资料,运用药物经济学成本-效果分析方法,对加替沙星与左氧氟沙星治疗下呼吸道感染进行药物经济学评价。结果与结论两组方案治疗下呼吸道感染的临床有效率、治愈率无显著性差异,但加替沙星组的细菌清除率优于左氧氟沙星组,左氧氟沙星的经济学成本优于加替沙星。

OBJECTIVE To evaluate the cost-effectiveness of gatifloxacin and levofloxacin in the treatment of patients with lower respiratory tract infection,promote rational use of the drugs and decrease the treatment cost.METHODS The cost-effectiveness was analyzed with medical cost-effectiveness analyzing method gatifloxacin and levofloxacin were compared in the treatment of patients with lower respiratory tract infection based on the published reference data.RESULTS and CONCLUSION There is no obvious difference between these two drugs in clinical effective rate and cure rate of patients with lower respiratory tract infection,but the bacteria clearance ratio of gatifloxacin was superior to that of levofloxacin.Cost-effectiveness ratio of levofloxacin is superior to that of gatifloxacin.