X线立体定向放射治疗在晚期胆管癌治疗中的价值

ANALYSIS ON THE EFFECT OF STEREOTACTIC RADIOTHERAPY IN THE TREATMENT OF ADVANCED BILE DUCT CANCER

目的评价Ｘ线立体定向放射治疗在晚期胆管癌治疗中的价值。方法晚期胆管癌４１例，胆肠内引流术后行立体定向放射治疗（ＳＲＴ）１６例，单纯行立体定向放射治疗１５例，单纯行胆肠内引流术１０例。Ｘ线立体定向放射治疗采用分次照射，方法为５Ｇｙ／次～６Ｇｙ／次，每周３次，总量达３５Ｇｙ～３６Ｇｙ。结果胆肠内引流术加立体定向放射治疗组、单纯立体定向放射治疗组及单纯胆肠内引流术组的１ａ生存率分别为６３％、４６．７％、０。

Objective To study the effect of stereotactic radiotherapy in the treatwent of advanced bile duct cancer. Methods From May 1996 to Octomber 1997,41 patients with advanced bile duct cancer were treated in our hospital,16 patients by stereotactic radiotherapy after bile duct cholangio jejunostomy, 15 by stereotactic radiotherapy alone and 10 by cholangio jejunostomy alone. In the stereotactic radiotherapy group,the method for stereotactic fractionated radiotherapy was 5 Gy～6 Gy per fraction,three times a week with the total dose of 35Gy～36Gy. Results The one year survival rate was 63% for cholangio jejunostomy plus stereotactic radiotherapy group,46.7% for stereotactic radiotherapy alone group, and 0 for cholangio jejunostomy alone group. Conclusions cholangio jejunostomy plus stereotactic radiotherapy is superior to stereotactic radiotherapy alone or cholangio jejunostomy alone in the treatment of advanced bile duct cancer.