105例分化型甲状腺癌的诊断和治疗

Diagnosis and Treatment of 105 Cases Differentiated Thyroid Carcinoma

目的:探讨分化型甲状腺癌的诊断和治疗。方法:回顾分析2006年1月至2009年8月行手术治疗的105例分化型甲状腺癌病例。结果:全组均行手术治疗和内分泌治疗。本组病例中,甲状腺乳头状癌69例(65.71%),甲状腺滤泡状癌36例(34.29%),并发淋巴结转移19例(17.14%)。手术方式为患侧腺叶及峡部切除26例,患侧腺叶和峡部及对侧大部分切除70例,全甲状腺切除并双侧颈淋巴结清扫术8例。全组无手术及住院期间死亡。结论:分化型甲状腺癌应根据病理组织类型、肿瘤大小、年龄和颈部淋巴结转移选择不同手术方式,术后辅以内分泌治疗。

Objective： To explore the analysis of clinical characteristics on differentiated thyroid carcinoma. Method： The records of 105 cases thyroid carcinoma treated between Jan. 2006 and Aug. 2009 were reviewed. Result： All of the 105 patients received operation and TSH suppression therapy. Histological examination after operation revealed papillary thyroid carcinoma in 69 cases（65.71%）,follicular thyroid carcinoma in 36 cases （34.29%） ,and lymph node metastasis was found in 19 cases （17.14%）. The operative procedure included excision of the affected lobe and isthmus in 26 cases, excision of the affected lobe,isthmus and greater part of the opposite lobe in 70 cases, total thyroidec- tomy and bilateral cervical dissection in 8 cases. There were no death with operation or in hospital. Conclusion： Surgical patterns for differentiated thyroid carcinoma should be based on pathological typing,tumor size,age,lymph node metastasis to the neck. The treatment is associated with postoperative endocrinotherapy.