血液灌流抢救急性中毒28例临床研究

The Emergent Hemoperfusion of 28 Patients with Acute Poisoning

目的:观察血液灌流抢救急性中毒的疗效。方法:28例中毒患者根据病情采用血液灌流每日1次,或每2h更换灌流器,连用2-3次,血液灌流次数平均为2次(1-5次),另27例中毒患者不用血液灌流治疗作为对照组。结果:血液灌流治疗患者的治愈率为92.9%,明显高于对照组70.37%(P<0.05)。昏迷清醒时间:血液灌流组8.6±3.5h,对照组12.6±5.8h(P<0.01)。平均住院:血液灌流组5.3±3.6d,对照组9.8±6.6d(P<0.05)。结论:血液灌流是治疗急性中毒的有效方法。

Objective： To study the efficacy of the hemoperfusion （HP） in the emergent treatment of acute poisoning. Method： 28 patients were treated with hemoperfusion according to the severity of the disease （HP group） once a day or continuously for two or three times a day. The hemoperfutor was changed every two hours. The hemoperfusion was performed twice a person on average （from once to five times for per person ） . The other 27 patients as controls were treated with non--hemoperfusion methods （control group）. Result： The cure rate of the HP group was 92.9%, which is significantly higher than 70. 37% of the control group （P〈0.05）. The recovery time from coma ：8. 6±3.5h in HP group, 12.6±5.8h in control group （P〈0.01）. The mean duration of hospitalization： 5.3±3. 6 days in HP group, 9.8~6.6 days in control group （P〈0.05）. Conclusion： He moperfusion is an effective method for treating acute poisoning.