个体化Q值引导LASIK治疗近视视觉质量分析

INVESTIGATION OF CLINICAL EFFECT OF Q-VALUE-GUIDED CUSTOMIZED LASIK FOR MYOPIA

目的比较Q值引导的个体化准分子激光原位角膜磨镶术(LASIK)与标准LASIK治疗近视的视觉质量。方法采用德国鹰视酷眼准分子激光机及可联机的角膜地形图对123例(246眼),屈光度在-1.50～-8.50D,散光在-0.50～-2.50DC的病人双眼同时治疗,其中右眼行Q值引导个体化LASIK切削程序治疗,Q值设置在-0.25～-0.50之间;左眼行标准LASIK切削程序治疗,术后随访>6个月。结果 Q值引导组术后裸眼视力、屈光度与标准组比较差异无显著性(P>0.05);两组术后Q值比较差异有显著性(t=40.86,P<0.05);Q值引导组术后视觉生活质量满意度高于标准组(χ2=16.97,P<0.05)。结论两组术后视力恢复快、安全稳定,其中Q值引导组保持了人眼角膜生理非球面性,病人视觉质量较好。

Objective To compare the improvement of vision in myopia treated by Q-value-guided customized LASIK （QLASIK） versus standard LASIK. Methods This study consisted of 123 patients with myopia （246 eyes, diopter from -1.50-8.50 D, astigmatism from -0.50-2.50 DC）, who were treated by ALLEGRETTO WAVEIM EYEQ and Wavelight-ALLEGRO TOPOLYZER. The patients＇ right eyes were treated by Q-value guided customized LASIK, while the left eyes by standard LASIK. Postoperative foliow-up was more than six months. Results No significant difference of uncorrected vision and dioper was observed between the Q-LASIK group and the standard LASIK group （P〉0.05）, while the postoperative Q-value of the two groups were significantly changed （t=40, 86,P〈0.05）. The rate of satisfied vision in the Q-LASIK group was markedly higher compared with that of the standard LASIK group （X^2= 16.97,P〈0.05）. Conclusion Both Q-LASIK and standard LASIK are safe, efficient for the treatment of myopia. The Q-LASIK maintains the physiological aspherieity of the human cornea, leading to a better improvement o~ vision.