参芪花粉片干预高原蛋白尿疗效观察

Observation of Shenqi Pollen Tablet Interfere in High Altitude Proteinuria

目的探寻高原蛋白尿的有效干预方法。方法将高原尿蛋白阳性的153例患者随机分为对照组(予安慰剂)、桂附地黄丸组、丹参滴丸组及参芪花粉组,15d为1疗程;比较各组高原蛋白尿疗效及转阴率。结果 3种药物治疗后尿蛋白均有降低,但参芪花粉组较桂附地黄丸组及丹参滴丸组尿蛋白下降更明显,参芪花粉组尿蛋白较对照组平均降低60μg/L,差异有统计学意义。结论桂附地黄丸、复方丹参滴丸和参芪花粉片对高原尿蛋白均有一定的治疗作用,但参芪花粉片对高原尿蛋白的疗效更确切,作用更明显。

Objective：To observe the effective intervention measure of high altitude proteinuria.Methods：153 cases with urine protein positive in high altitude area were randomly divided into the control group and the treatment group,which were subdivided into the Guifudihuang Pills group,the Danshen Pilulae group and Shenqi Pollen Tablet group.After 15 days for a course,the efficacy and the negative conversion rate of high altitude proteinuria were analyzed with tracing observation.Results：After treatment,levels of urine protein were decreased in 3 groups.Moreover,the level in the Shenqi Pollen Tablet was reduced more significantly than that in other groups.Compared with the control group,the average reduction of the urine protein was 60μg/L in the Shenqi Pollen Tablet group.There was a statistical difference in two groups.Conclusion：There are some therapeutical effects of the high altitude proteinuria in above three drugs,but there is more definite and more effective in the Shenqi Pollen Tablet in this disease.