1Levy MM, Fink MP, Marshall JC, et al. 2001SCCM/ESICM/ ACCP/ ATS/SIS international sepsis definitions conference[J]. Crit Care Med, 2003,31(4): 1250-1256.
3Siddiqui AM, Cui X, Wu R, et al. The anti inflammatory effect of sepsis is mediated by up-regulation of peroxisome proliferator activated receptor-gamma[J]. Crit Care Med, 2006, 34(?): 1874-1882.
1Casey L C, Balk R A, Bone R C. Plasma cytokine and endotoxin concentrations correlate with survival in patients with the sepsis syndrome[J]. Ann Intern Med, 1993, 119: 771-778.
2Panacek E. New direction in severe sepsis research, including IL-6 stratification and TNF - alpha blockade: program and abstracts of the 30th international educational and scientific symposium of the society of critical care medicine[J]. Califomia: San Francisco, 2001. 10- 14.
3American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference. Definitions for the use of innovative therapies in sepsis[J]. Crit Care Med:1992, 20:864-S74.
4Assicot M, Gendrel D, Carsin H, et al . High serum procalcitonin concentrations in patients with sepsis and infection [ J ]. Lancet, 1993,341:515-518.
5Nelyn E S, Whang K T, White J C. Mortality is increased by procalcitonin and decreased by an antiserum reactive to procalcitonin in experimental sepsis[J]. Crit Care Med, 1998, 26:1001 - 1006.
6Hack C E, de Groot E R, Felt- Bersma R J, et al. Increased plasma concentrations of interleukin - 6 in sepsis[J]. Blood, 1989, 74:1704 -1710.
7Spittler A, Razenberger M, Kupper H, a al. Relationship between interleukin- 6 plasma concentration in patients with sepsis, monocyte phenotype, monocyte phagocytic properties, and cytokine production[J]. Clin Infect Dis, 2000, 31: 1338- 1420.
8Bernard G R, Vincent J L, Laterre P F, etal. Efficacy and safety of recombinant human activated protein C for severe sepsis [ J ]. N Engl J Med, 2001, 344: 699-709.
