对乙酰氨基酚片微生物限度检查方法的验证

Valiuation of Microbial Limit Test for Paracetamol

目的:验证对乙酰氨基酚片的微生物限度检查方法是否适用于该供试品的检查。方法:细菌计数采用低速离心-培养基稀释法,霉菌及酵母菌计数按常规检查法,控制菌按常规检查法。结果:稀释剂对照组的菌回收率大于70%,试验组的菌回收率大于70%;阴性对照组未检出阴性对照菌,试验组检出阳性试验菌。结论:可以用该微生物限度检查法进行对乙酰氨基酚片的检查。

Objective：To test wheather it is feasible to medium Paraeetamol by Valiuation of Microbial Limit. Methods： Diluling Palate Method for Bacteria Count. Conventional Method for Mold and Yeast Count. Conventional Method for Control Bacterial Count. Results：the recovery of Bacterium in Control Group is more than 70%. The recovery of Bacterium in Test Group is more than 70%. No Negative Control Bacterium in Negative Control Group. Conclusion：it is feasible to test Paracetamol by Valiuation of Microbial Limit Method.